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--- md_biochemistry [2026/02/25 10:58]
resident [Seminar and Micro- Teaching For MD Biochemistry]
+++ md_biochemistry [2026/06/26 13:25] (current)
admin
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 |31|:::| |
 |24|<html><span style="font-size:150%;">Dr Janki Sonagra</span></html> |Ammonia Detoxification|{{ ::ammonia_detoxification_2_2_.pptx |}}|
-|25|:::|Prion Disease |[[https://docs.google.com/presentation/d/15jx6CwLXlqoAOEvX0uWkMF1tEPY38PIv/edit?usp=drive_link&ouid=105726813387160537689&rtpof=true&sd=true|Prion Disease]] |
+|25|:::|Prion Disease |{{ ::prion_disease.pptx.pdf |}}|
 |26|:::|Tertery & Quaternary Protein structure |{{ :protein_structure_1_1_.pptx.pdf |}}|
 |27|:::|Arginine Metabolism|{{ ::arginine_metabolism_2_.pptx.pdf |}}|
@@ Line 50: / Line 50: @@
 |29|:::|IQC|{{ ::iqc_janki.ppt.pdf |}}|
 |30|:::| |
-|31|:::| |
+|31|<html><span style="font-size:150%;">Dr Nishit Chudasama</span></html> | |
+|31|<html><span style="font-size:150%;">Dr Shivam</span></html> | |
 =====Model Questions List For MD Biochemistry=====
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   - Technical requirement to maintain integrity of the sample between sample collection to analysis as per clause 7.2.5 and 7.2.7.3 of ISO 15189:2022 and expected risk on sample stability for biochemistry analytes.
   - Write two enzyme with it’s therapeutic use with it’s mechanism of action.
+  - ''Define HIL indexation and it’s significant in clinical biochemistry laboratory''
+  - ''Metabolic and endocrine changes during fasting condition and during exercise''
+  - ''Fact and Myth of the use of olive oil in food preparation.''
+  - ''Biochemical impact of different food additive and adulteration.''
+  - ''Structure and Function of Gluten , especially as food protein.''
+  - ''Molar absorptivity of NADh and calculation of enzyme factors''
+  - ''Biochemical explanation of pulmonary embolism in deep sea divers''
+  - ''Requirement as per ISO 15189:2022 for POCT.''
@@ Line 149: / Line 161: @@
   - Biochemical basis of etiology, diagnosis and treatment of unconjugated neonatal hyperbilirubinemia.
   - Amphibolic role of TCA cycle.
   - Metabolic changes during exercise.
   - Biochemistry basis of change in enzyme activity due to change in pH and temperature.
   - Biochemical explanation of galactosemia
@@ Line 183: / Line 195: @@
   - ATP IV Hypercholesterolemia diagnostic guidline
   - beta thalassemia – genetics, pathogenesis, diagnosis
+  - ''Define tertiary structure of protein with domain and chaperon. Explain pathogenesis of prion disease with example of amyloidosis.''
+  - ''Enumerate cholesterol synthesis with regulation. Describe type of dyslipidemia. Explain framingham risk scores for cardiovascular risk.''
+  - ''Metabolic and neuro-transmitter alteration during alcohol addiction and withdrawal.''
+  - ''Classify obesity. Explain endocrinal pathogenesis of obesity.''
+  - ''Function and significant of PTH and Intact PTH.''
+  - ''Effect of cirrhosis of liver on metabolism and  digestion – absorption''
+  - ''Genetic regulation of haemoglobin synthesis and impact of therapeutic drugs & metal on it.''
+  - ''Explain “Role of vitamins on metabolism” (with examples)''
+  - ''Alteration in blood buffer and renal buffer in case of extensive interstitial lung disease.''
 |<html> <span style="color:   #700800   ;font-size:125%;">2024</span> </html>|<html> <span style="color:   #700800   ;font-size:125%;">List of Model Question for Paper-3 - Molecular Biology , Immunology and Cancer</span> </html>|
@@ Line 214: / Line 239: @@
   - Write note somatic hyper mutation and iso-type switching of immunoglobin.
   - Regulation of m-RNA stability
+  - ''Type and significance of all the type of RNA. Clinical co-relation of RNA in pathogenesis of cancer , atherosclerosis and Age related Macular Degeneration (AMD)''
+  - ''Viral integration and transposons in human genome. Molecular impact of anti-viral drugs - Acylovir.''
+  - ''Regulation of eukaryotic gene expression''
+  - ''Journey of human genome evolution from mutation to substitution.''
+  - ''Tumor Supressor Gene - BRCA and p53''
+  - ''Meiosis vs Mitosis''
+  - ''Molecular defect in cystic fibrosis''
+  - ''Quantitative Real time PCR''
+  - ''DNA dependent DNA polymerase and DNA ligase.''
 |<html> <span style="color:   #700800   ;font-size:125%;">2024</span> </html>|<html> <span style="color:   #700800   ;font-size:125%;">List of Model Question for Paper-4 - Technique in experimental biochemistry , Recent advances</span> </html>|
@@ Line 295: / Line 333: @@
   - Write performance validation protocol for these specified resource ( instrument / reagent / consumable)
   - Write a consistent quality policy and objective with defined quality indicator, for your laboratory.
+  - ''Enumerate analytical methods with it’s principle , significant and limitation of creatinine estimation and eGFR.''
+  - ''Definition of quality indicator with it’s standard requirements. Define quality indicator for period of sample collection to sample receipt (minimum four QI ) and sample storage (minimum four QI ) with process of it’s monitoring and measuring elements.''
+  - ''Principle and utility of Fourier Transform Infrared (FTIR) spectroscopy in clinical biochemistry laboratory. Approach to validate the result of FTIR.''
+  - ''Structure and component of “Foundation Course” for First year Indian Medical Graduate (IMG)''
+  - ''AETCOM''
+  - ''Document Control and Control of Record as per ISO 15189:2022''
+  - ''Use of moving average of patient data as IQC alternative''
+  - ''Delta Bilirubin - Define and Clinical significant.''
+  - ''Component and Principle of Flame Photometer''
+  - ''Mechanism , clinical utility and biochemical adverse event with use of GLP-1 analogues''
+  - ''Sample acceptance exception in case of wrong vacuette (Write minimum 4 scenario)''
 |<html> <span style="color:   #700800   ;font-size:125%;">2024</span> </html>|<html> <span style="color:   #700800   ;font-size:125%;">Drugs To Read With Biochemical Mechanism</span> </html>|
@@ Line 321: / Line 374: @@
   - Tocilizumab
   - Hydroxychloroquine
+  - Rifaximin